Leading Edge Genomic Services & Solutions



Novogene is a leading provider of cutting-edge NGS services that generates the highest quality data in this market. The results that we have generated have been included in a substantial number of published articles in prestigious journals. Below is a selected list of publications.


Adaptive introgression underlies polymorphic seasonal camouflage in snowshoe haresMatthew R. Jones, et al.Science6/22/2018
Genome diversity of the potatoBinquan Huang, et al.Proceedings of the National Academy of Sciences of the United States of America6/22/2018
HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infectionFubing Li, et al.The Journal of Clinical Investigation6/19/2018
Efficient RNA drug delivery using red blood cell extracellular vesiclesWaqas Muhammad Usman, et al.Nature Communications6/15/2018
Srsf2P95H initiates myeloid bias and myelodysplastic/myeloproliferative syndrome (MDS/MPN) from hemopoietic stem cellsMonique F. Smeets, et al.Blood6/14/2018
Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cellsJuliane Hitzel, et al.Nature Communications6/12/2018
An Orc1/Cdc6 ortholog functions as a key regulator in the DNA damage response in ArchaeaMengmeng Sun, et al.Nucleic Acids Research6/7/2018
Spatial transcriptomic survey of human embryonic cerebral cortex by single-cell RNA-seq analysisXiaoying Fan, et al.Cell Research6/4/2018
Serpin Facilitates Tumor-Suppressive Cell Competition by Blocking Toll-Mediated Yki Activation in DrosophilaMitsuko Katsukawa, et al.Current Biology6/4/2018
RNA N6-methyladenosine methyltransferase-like 3 promotes liver cancer progression through YTHDF2-dependent posttranscriptional silencing of SOCS2Mengnuo Chen, et al.Hepatology6/1/2018
CREPT facilitates colorectal cancer growth through inducing Wnt/β-catenin pathway by enhancing p300-mediated β-catenin acetylationYanquan Zhang, et al.Oncogene6/1/2018
Opposing roles of miR‐294 and MBNL1/2 in shaping the gene regulatory network of embryonic stem cellsDa‐Ren Wu, et al.EMBO reports6/1/2018
Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editingJoseph Hawksworth, et al.EMBO Molecular Medicine6/1/2018
Opposite Roles of Salicylic Acid Receptors NPR1 and NPR3/NPR4 in Transcriptional Regulation of Plant ImmunityYuli Ding, et al.Cell5/31/2018
Precise control of SCRaMbLE in synthetic haploid and diploid yeastBin Jia, et al.Nature Communications5/22/2018
Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiotaJunyue Xing, et al.Nature Communications5/22/2018
c-Myc inhibits myoblast differentiation and promotes myoblast proliferation and muscle fibre hypertrophy by regulating the expression of its target genes, miRNAs and lincRNAsWen Luo, et al.Cell Death & Differentiation5/21/2018
Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaksNobuhiko Muramoto, et al.Nature Communications5/18/2018
Circadian regulator NR1D2 regulates glioblastoma cell proliferation and motilityMin Yu, et al.Oncogene5/18/2018
Pseudomonas aeruginosa MutL promotes large chromosomal deletions through non-homologous end joining to prevent bacteriophage predationMengyu Shen, et al.Nucleic Acids Research5/18/2018
Mapping the Mouse Cell Atlas by Microwell-SeqXiaoping Han, et al.Cell5/17/2018
Melatonin attenuates osteosarcoma cell invasion by suppression of C‐C motif chemokine ligand 24 through inhibition of the c‐Jun N‐terminal kinase pathwayKo‐Hsiu Lu, et al.Journal of Pineal Research5/16/2018
Genome sequence of the progenitor of wheat A subgenome Triticum urartuHong-Qing Ling, et al.Nature5/9/2018
Resequencing a core collection of upland cotton identifies genomic variation and loci influencing fiber quality and yieldZhiying Ma, et al.Nature Genetics5/7/2018
Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune ResponseMinghong Jiang, et al.Cell5/3/2018
Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAsYunfang Zhang, et al.Nature Cell Biology5/1/2018
Mechanistic exploration of cancer stem cell marker voltage-dependent calcium channel α2δ1 subunit-mediated chemotherapy resistance in small cell lung cancerJiangyong Yu, et al.Clinical Cancer Research5/1/2018
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumorsArnoud Boot, et al.Genome Research5/1/2018
The Gastrodia elata genome provides insights into plant adaptation to heterotrophyYuan Yuan, et al.Nature Communications4/24/2018
OCEAN-C: mapping hubs of open chromatin interactions across the genome reveals gene regulatory networksTingting Li, et al.Genome Biology4/24/2018
Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosisZhongcheng Zhou, et al.Nucleic Acids Research4/20/2018
Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T CellsJing Li, et al.Immunity4/17/2018
HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma developmentLiang Zhou, et al.Nature Communications4/16/2018
Contraction of basal filopodia controls periodic feather branching via Notch and FGF signalingDongyang Cheng, et al.Nature Communications4/9/2018
Mapping human pluripotent stem cell differentiation pathways using high throughput single-cell RNA-sequencingXiaoping Han, et al.Genome Biology4/5/2018
Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarctionXin Zhou, et al.Microbiome4/3/2018
Plant Genome Editing Using FnCpf1 and LbCpf1 Nucleases at Redefined and Altered PAM SitesZhaohui Zhong, et al.Molecular Plant3/20/2018
Rapid Global Spread of wRi-like Wolbachia across Multiple DrosophilaMichael Turelli, et al.Current Biology3/19/2018
Single-cell RNA-seq analysis unveils a prevalent epithelial/mesenchymal hybrid state during mouse organogenesisJi Dong, et al.Genome Biology3/14/2018
Genic C-Methylation in Soybean Is Associated with Gene Paralogs Relocated to Transposable Element-Rich PericentromeresMoaine El Baidouri, et al.Molecular Plant3/5/2018
Whole-exome sequencing reveals the origin and evolution of hepato-cholangiocarcinomaAnqiang Wang, et al.Nature Communications3/1/2018
Long noncoding RNA pancEts-1 promotes neuroblastoma progression through hnRNPK-mediated β-catenin stabilizationDan Li, et al.Cancer Research3/1/2018
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiotaWenkai Ren, et al.Journal of Pineal Research3/1/2018
A set of regulatory genes co-expressed in embryonic human brain is implicated in disrupted speech developmentElse Eising, et al.Molecular Psychiatry2/20/2018
Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer’s disease pathogenesisXiaopu Zhou, et al.Proceedings of the National Academy of Sciences of the United States of America2/20/2018
Genomic Analyses Yield Markers for Identifying Agronomically Important Genes in PotatoYangping Li, et al.Molecular Plant2/5/2018
Abscisic Acid Signaling Inhibits Brassinosteroid Signaling through Dampening the Dephosphorylation of BIN2 by ABI1 and ABI2Haijiao Wang, et al.Molecular Plant2/5/2018
Age-associated microbiome shows the giant panda lives on hemicelluloses, not on celluloseWenping Zhang, et al.ISME Journal2/1/2018
MinION-based long-read sequencing and assembly extends the Caenorhabditis elegans reference genomeJohn R Tyson, et al.Genome Research2/1/2018
A genome for gnetophytes and early evolution of seed plantsTao Wan, et al.Nature Plants1/29/2018
CD70, a novel target of CAR T-cell therapy for gliomasLinchun Jin, et al.Neuro-Oncology1/10/2018
Single-cell DNA methylome sequencing of human preimplantation embryosPing Zhu, et al.Nature Genetics1/1/2018